Ordering of polymorphic markers in the chromosome region 3p21

Starting from five markers, with a well-defined order from distal to proximal 3p21, nine other markers could be inserted in this 3p21 map. Five were precisely mapped genetically. The other markers were ordered by FISH and/or deletion hybrid mapping. The overall 3p21 order from distal to proximal is as follows: D3S1298-D3S1260-(D3S966, D3S1448 (= D3S1449)-D3S1029-D3S32-D3S643-D3F15S2 -D3S2968-D3S1235-D3S1289-D3S1447-D3S1295.     

Computer simulation of injection molding

The injection-molding process consists of three consecutive stages: filling, packing, and cooling. In order to obtain some insight into the phenomena involved in the process, and particularly in order to evaluate the moldability of certain resins and to predict the microstructure and properties of products molded therefrom, a number of workers have employed a variety of techniques based on mathematical simulation of the process. Mathematical simulation involves writing the relevant continuity, momentum, and energy equations governing the system, with appropriate boundary and initial conditions representing the prevailing conditions in the cavity and delivery channels. In order to obtain meaningful solutions to the above equations, detailed information is required regarding the thermodynamic, thermal, and rheological properties of the resin. Moreover, the prediction of the microstructure and ultimate properties of the molded article requires a knowledge of the morphological, crystallization, and orientation phenomena that take place under the influence of the thermo-mechanical history experienced by the resin. The complexity of the equations involved results in the utilization of a number of simplifying assumptions and the resort to computer simulation and numerical solutions of these equations. A variety of numerical schemes based on finite difference and finite element methods has been employed by various researchers.     

Capillary viscometry: A complete analysis including pressure and viscous heating effects

Capillary viscometers have been used extensively, because of their simplicity and reliability, to measure the viscosity of fluids over a wide range of shear rates. However, in capillary flow, the shear rate is not uniform throughout the capillary, a pressure gradient is established in the direction of flow, and the temperature of the fluid is nonuniform due to viscous dissipation. In the present work, a general, simple and practical method is proposed for correcting for the effects of pressure variation and viscous dissipation in determining the viscosity of polymer melts at high pressures. The method essentially involves the estimation of temperature, pressure, shear rate, and shear stress under a variety of experimental conditions at a predetermined point in the capillary. As such, it may be considered as a generalized extension of the classical Rabinowitsch-Mooney method for estimating true viscosity in capillary flow.     

A software reliability engineering practice

A recently adopted best current practice (BCP) at AT&T involving performing software reliability engineering (SRE) tasks over the software life cycle is discussed. Software reliability is defined as the capability of a software product to operate failure-free for a given period under specified operating conditions. The support mechanisms for the SRE BCP are described     

Effect of the vascular endothelium on norepinephrine-induced contractions in uterine radial arteries from the nonpregnant and pregnant human uterus

OBJECTIVE: Our purpose was to investigate the role of the endothelium in the human uterine arterial response to norepinephrine in the nonpregnant and pregnant states. STUDY DESIGN: Tissue was obtained from six pregnant and six nonpregnant women undergoing cesarean section or hysterectomy. Uterine radial arteries were isolated and subjected to norepinephrine dose-response curves with and without intact endothelium. RESULTS: Responses were obtained over a dose range of 10(-8) to 10(-4) norepinephrine. Initially there was no difference between vessels from pregnant and nonpregnant patients, but removal of the endothelium significantly increased the response in vessels from pregnant women. Addition of nitro-L-arginine methyl ester when the endothelium was intact did not alter the dose-response curves. CONCLUSIONS: In pregnancy human uterine radial arteries are more sensitive to norepinephrine than during the nonpregnant state. This increase is countered by an endothelium-derived relaxing factor. The factor is unlikely to be nitric oxide.     

丙烯酸酯防钻绒涂层剂的合成研究

介绍了一种乳液聚合方法,通过种子乳液聚合,选用合适的聚合单体,探讨了引发剂和乳化剂的品种及用量对聚合反应的影响,最终确定了反应工艺条件,合成了一种丙烯酸酯防钻绒涂层剂。     

Effect of carbohydrate supplementation provided through drinking water during feed withdrawal on meat and liver colours in broilers

BACKGROUND: The effect of saccarose supplementation provided through drinking water during feed withdrawal on meat and liver colour was investigated in a total of 50 broilers (five floor pens with 10 broilers) at 43 days. Treatments consisted of: (1) full‐fed control broilers fed the standard broiler diet and water for the full 10 h (control); (2) fasted broilers receiving only water (FW); (3) 1 g (0.01SW); (4) 2 g (0.02SW); and (5) 3 g (0.03SW) saccarose L^?1 supplemented water for the 10 h. The CIE colour values representing lightness (L*), redness (a*), and yellowness (b*) were measured on raw livers, breast and thigh meats. RESULTS: Full‐fed broilers had lower dressing percentage, higher abdominal fat and liver yield and lighter thigh meat coloration than the FW birds (P < 0.05). The 0.02SW and 0.03SW resulted in live shrinks that were lower (P < 0.05) than those found in FW broilers. The 0.02SW and 0.03SW resulted in liver colours that were lighter than those found in FW and 0.01SW birds but darker than from control birds (P < 0.05). CONCLUSION: It was concluded that saccarose supplementation during feed withdrawal appears to have a measurable impact on live shrink, and lightness of liver and thigh meat colour in broilers. Copyright © 2007 Society of Chemical Industry